Peptide Database

MK-677 is a potent oral growth hormone secretagogue that mimics ghrelin, producing sustained 24-hour elevations in GH and IGF-1 without suppressing natural production.

VIP is a 28-amino-acid neuropeptide that functions as a potent immunomodulator, vasodilator, and neuroprotector, gaining attention for treating CIRS/mold toxicity via Dr. Shoemaker protocols.

HGH Fragment 176-191 is the fat-reducing portion of the growth hormone molecule, shown to be 12.5x more potent than regular GH for fat loss while having no effect on blood sugar or cell proliferation.

Tesofensine is a triple monoamine reuptake inhibitor originally developed for neurological diseases, discovered to cause dramatic weight loss — averaging 12.8 kg in 6 months at therapeutic doses.

AICAR is an AMP-activated protein kinase (AMPK) agonist that mimics the metabolic effects of exercise, enhancing endurance, fat oxidation, and mitochondrial biogenesis without physical training.

IGF-1 DES is a truncated IGF-1 analog missing three N-terminal amino acids, making it approximately 10x more potent than regular IGF-1 because it does not bind to IGF binding proteins.

5-Amino-1MQ is a small molecule NNMT inhibitor that redirects cellular metabolism toward increased energy expenditure and reduced fat accumulation, representing a novel non-hormonal approach to weight management.

Davunetide is an eight-amino-acid peptide, also known as NAP, derived from the ADNP protein. It has been studied for microtubule stabilization, neuroprotection, and potential effects on cognition in neurodegenerative and injury models.

Glycyl-L-prolyl-L-glutamic acid (GPE) is a tripeptide derived from IGF-1 processing that has been studied for neuroprotection and synaptic support. It has been explored in models of learning, memory retention, and injury-related cognitive decline.

Irisin is a cleavage product of FNDC5 that has been studied for exercise-linked improvements in glucose homeostasis and energy expenditure. It can influence AMPK, SIRT1, and PGC-1α signaling in metabolic tissues.

Omentin-1 is an adipokine linked to improved insulin sensitivity and healthier lipid handling. Experimental work suggests it can enhance glucose uptake through AMPK-dependent signaling.

Adiponectin is a 244-amino-acid adipokine that improves insulin sensitivity and fatty-acid oxidation. It is one of the best-known upstream activators of AMPK in liver and skeletal muscle.

An endogenous opioid-like neuropeptide that acts at the NOP receptor and has bidirectional effects on pain processing. In many neuropathic pain models it reduces allodynia and hyperalgesia, making it a key research peptide for pain circuits.

A 31-amino-acid peptide released with insulin from proinsulin processing. It has been studied in diabetic neuropathy for nerve-conduction and symptom improvements, making it relevant to neuropathic pain research.

A synthetic 24-amino-acid fragment of ACTH used clinically in adrenal testing. It has also been used off-label in refractory migraine/status migrainosus, making it a real peptide of interest in headache care.

A constitutively expressed epithelial antimicrobial peptide that contributes to innate oral defense. It is found in oral tissues and saliva and helps control bacterial and fungal colonization.

A naturally occurring salivary phosphopeptide that binds hydroxyapatite and helps maintain calcium phosphate supersaturation in the mouth. It is important for enamel pellicle formation and inhibition of pathologic mineral deposition.

A salivary histidine-rich peptide with strong antifungal and antimicrobial properties in the oral cavity. It is widely studied for oral candidiasis and mucosal defense.

A synthetic self-assembling peptide designed to form a scaffold in demineralized enamel and promote biomimetic remineralization. It is one of the best-known peptide approaches for early caries lesion repair.

An endogenous 27-amino-acid peptide released from the duodenum in response to acidic chyme. It stimulates pancreatic bicarbonate secretion and supports digestion in the upper GI tract.

A synthetic 16-amino-acid peptide and GC-C agonist related to uroguanylin. It is used to treat chronic idiopathic constipation and IBS-C by promoting intestinal secretion and softer stools.

A synthetic 14-amino-acid guanylate cyclase-C agonist used for chronic constipation and IBS-C. It increases intestinal fluid secretion and can improve stool frequency while indirectly shaping the luminal environment.

A mitochondria-targeted tetrapeptide that stabilizes cardiolipin and reduces mitochondrial oxidative stress. It is not a classic anabolic peptide, but it can support muscle endurance and recovery by improving mitochondrial efficiency.

A 51-amino-acid peptide hormone that strongly suppresses muscle protein breakdown and promotes glucose and amino acid uptake. In research and clinical settings it is primarily used for glycemic control, but it is also one of the most established anti-catabolic signals in skeletal muscle.