Cholecystokinin-8
Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)
DY(SO3H)MGWMDF-NH2 Amino Acids · MW: 1143.2 Da
Amino Acids
DY(SO3H)MGWMDF-NH2
Molecular Weight
1143.2 Da
Half-life
1-2 min
Research Score
5.0
Studies
97
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Cholecystokinin-8?
A bioactive fragment of cholecystokinin that is widely used to study GI hormone signaling. It stimulates gallbladder contraction and pancreatic enzyme secretion and is a major satiety-related gut peptide.
Key Benefits & Mechanisms
gallbladder contraction
pancreatic enzyme release
satiety signaling
Research Summary
CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.
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Endocrine Peptides