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Endocrine PeptidesEndogenous

GLP-1(7-36) amide

Glucagon-like peptide-1 (7-36) amide

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 Amino Acids · MW: 3297.7 Da

Amino Acids

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2

Molecular Weight

3297.7 Da

Half-life

1-2 min

Research Score

5.0

Studies

99

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is GLP-1(7-36) amide?

An endogenous incretin peptide released from intestinal L-cells after nutrient intake. It enhances glucose-dependent insulin secretion and slows gastric emptying, making it one of the most important gut hormones in metabolism research.

Key Benefits & Mechanisms

glucose-dependent insulin secretion

gastric emptying delay

satiety signaling

Research Summary

One of the best-studied gut hormones, with strong evidence for incretin biology and appetite regulation. Native GLP-1 is rapidly degraded by DPP-4, which is why its biology is central to endocrine and metabolic pharmacology.