Peptide Database

BPC-157 (Body Protection Compound-157) is a pentadecapeptide composed of 15 amino acids. It is a partial sequence of the body protection compound discovered in and isolated from human gastric juice. Extensive research demonstrates remarkable healing effects on tendons, muscles, the nervous system, and gastrointestinal tissue.

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring peptide present in virtually all human and animal cells. It plays a crucial role in tissue repair, wound healing, and cell migration. TB-500 promotes tissue regeneration and reduces inflammation.

Ipamorelin is a selective growth hormone secretagogue that stimulates natural GH release without significantly affecting cortisol or prolactin levels. It is considered one of the safest and most selective GHRPs available.

IGF-1 LR3 is a modified version of IGF-1 with 13 times the half-life of native IGF-1. It promotes anabolic signaling, muscle hyperplasia, and cellular repair with extended bioavailability.

Oxytocin is a naturally occurring nonapeptide hormone produced in the hypothalamus. Known as the "bonding hormone," it plays crucial roles in social behavior, emotional regulation, trust, and pair bonding. FDA-approved (Pitocin) for labor induction. Being studied for autism, anxiety, and PTSD.

Thymosin Beta-4 (TB4) is a naturally occurring 43-amino acid peptide present in nearly all human cells. It is the primary G-actin sequestering molecule in cells and plays fundamental roles in tissue repair, cell migration, blood vessel formation, and anti-inflammation. TB-500 is its synthetic fragment.

Tirzepatide is a first-in-class dual GIP and GLP-1 receptor agonist. FDA-approved as Mounjaro (diabetes) and Zepbound (weight management). It offers superior weight loss compared to GLP-1-only agonists by targeting two incretin pathways simultaneously.

Thymosin Alpha-1 is a naturally occurring 28-amino acid peptide originally isolated from the thymus gland. It modulates immune response, enhances T-cell function, and is FDA-approved in some countries for hepatitis B/C treatment.

Semaglutide is a GLP-1 receptor agonist with proven efficacy for weight management and glycemic control. FDA-approved as Ozempic (diabetes) and Wegovy (weight management), it mimics the incretin hormone GLP-1 to regulate appetite and blood sugar.

GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It declines with age and plays critical roles in wound healing, tissue remodeling, collagen synthesis, and anti-inflammatory signaling. Extensively studied for skin rejuvenation and anti-aging applications.

Tesamorelin is an FDA-approved synthetic analog of growth hormone-releasing hormone (GHRH). Approved as Egrifta for HIV-associated lipodystrophy, it reduces visceral adipose tissue while maintaining peripheral fat and improving body composition. Produces physiological GH release.

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH) identical to the natural hormone produced by the hypothalamus. It stimulates the release of LH and FSH from the pituitary gland, supporting natural testosterone production and fertility. Often used in TRT and PCT protocols.

Semax is a synthetic heptapeptide analog of ACTH(4-7) developed at the Institute of Molecular Genetics in Russia. It enhances cognitive function, memory, and neuroprotection through BDNF upregulation and modulation of serotonergic and dopaminergic systems. Approved in Russia as a nootropic and neuroprotective agent.

PT-141 (Bremelanotide) is a melanocortin receptor agonist FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women. Unlike PDE5 inhibitors, it works through the central nervous system to enhance sexual arousal and desire. Derived from Melanotan II research.

Cerebrolysin is a mixture of low-molecular-weight neuropeptides and free amino acids derived from porcine brain tissue. It has neurotrophic properties similar to naturally occurring nerve growth factors. Approved in many countries for stroke recovery, traumatic brain injury, and dementia.

Sermorelin is a synthetic analog of the first 29 amino acids of GHRH. Previously FDA-approved as Geref for pediatric GH deficiency, it stimulates natural, pulsatile GH release from the pituitary. Widely used in anti-aging medicine for its physiological approach to GH optimization.

Retatrutide is a first-in-class triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. In Phase II trials, it achieved up to 24% body weight loss, surpassing both semaglutide and tirzepatide. It represents the next evolution in incretin-based therapies.

Liraglutide is an FDA-approved GLP-1 receptor agonist available as Victoza (diabetes) and Saxenda (weight management). It was the first GLP-1 agonist approved specifically for chronic weight management. While newer agents show greater efficacy, liraglutide paved the way for the GLP-1 revolution.

CJC-1295 is a modified GHRH analog with an extended half-life due to Drug Affinity Complex (DAC) technology. It promotes sustained, pulsatile GH release, improving body composition, recovery, and sleep quality.

GHRP-6 is a hexapeptide that stimulates the ghrelin receptor to promote growth hormone release. It is one of the earliest and most studied GH secretagogues, known for significant GH pulse induction and appetite stimulation.

GHK is the copper-free form of the well-known GHK-Cu tripeptide. It naturally occurs in human plasma and declines significantly with age. Even without copper, GHK influences gene expression of over 4,000 human genes, many involved in tissue remodeling, DNA repair, and antioxidant defenses.

LL-37 is the only cathelicidin antimicrobial peptide found in humans. It plays a critical role in innate immune defense against bacterial, viral, and fungal infections. Beyond antimicrobial activity, it modulates inflammation, promotes wound healing, and influences adaptive immunity.

GHRP-2 (Pralmorelin) is a synthetic hexapeptide that stimulates growth hormone release through the ghrelin receptor. It produces stronger GH release than GHRP-6 with less appetite stimulation. Approved in Japan as a diagnostic agent for GH deficiency.

Hexarelin is a synthetic hexapeptide growth hormone secretagogue and ghrelin receptor agonist. It is one of the strongest GHRPs available, producing the highest GH release among its class. It also has notable cardioprotective properties independent of GH release.

Matrixyl (Palmitoyl Pentapeptide-4) is one of the most well-studied and commercially successful anti-aging peptides. It stimulates collagen I, III, and IV production, as well as fibronectin synthesis. Clinical studies show it can reduce wrinkle depth comparable to retinol but without irritation.

Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH). It stimulates melanin production for skin tanning, provides photoprotection, and has demonstrated aphrodisiac properties in research.

Selank is a synthetic peptide analog of the naturally occurring tetrapeptide tuftsin. Developed in Russia, it has anxiolytic and nootropic properties. It modulates the expression of brain-derived neurotrophic factor (BDNF) and serotonin.

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that concentrates in the inner mitochondrial membrane. It stabilizes cardiolipin, improves electron transport chain efficiency, and reduces reactive oxygen species. Being developed for mitochondrial myopathies and heart failure.

CagriSema is a fixed-dose combination of cagrilintide (a long-acting amylin analog) and semaglutide (GLP-1 agonist). By targeting two complementary satiety pathways, it achieves superior weight loss compared to either component alone. Phase III trials show it may become the most effective obesity treatment.

Exenatide is a GLP-1 receptor agonist originally derived from the saliva of the Gila monster lizard. FDA-approved as Byetta (twice daily) and Bydureon (once weekly) for type 2 diabetes. It was the first commercially available GLP-1 receptor agonist and paved the way for the entire drug class.

NA-Semax is the acetylated and amidated version of Semax with enhanced stability and bioavailability. The modifications extend its half-life and improve nasal absorption. It retains all nootropic and neuroprotective properties of Semax while requiring less frequent dosing.

Epithalon is a synthetic tetrapeptide that activates telomerase, the enzyme responsible for maintaining telomere length. Originally developed by Russian scientist Vladimir Khavinson, it is studied for anti-aging and longevity applications.

Survodutide is a dual GLP-1 and glucagon receptor agonist being developed by Boehringer Ingelheim. It has shown remarkable results for both weight loss and non-alcoholic steatohepatitis (NASH/MASH), significantly reducing liver fat content while achieving substantial weight loss.

AOD-9604 is a modified fragment of human growth hormone (HGH fragment 177-191) specifically designed for fat metabolism. It stimulates lipolysis and inhibits lipogenesis without affecting blood sugar or tissue growth, making it a targeted fat-loss peptide without typical GH side effects.

NA-Selank is the acetylated and amidated version of Selank, designed for enhanced stability and bioavailability. The N-acetyl modification protects against enzymatic degradation, resulting in longer-lasting effects. It maintains all the anxiolytic and cognitive benefits of Selank with improved pharmacokinetics.

VIP is a 28-amino acid neuropeptide found throughout the body. It regulates smooth muscle activity, epithelial cell secretion, and blood flow. In recent years, it has gained attention for treating chronic inflammatory response syndrome (CIRS), mold illness, and neuroinflammation.

MOTS-c is a mitochondrial-derived peptide that regulates metabolic homeostasis and exercise physiology. It activates AMPK, improves insulin sensitivity, and mimics the metabolic effects of exercise. Discovered at USC, it represents a new class of mitochondrial signaling peptides.

Kisspeptin-10 is a fragment of the kisspeptin hormone that plays a master regulatory role in the hypothalamic-pituitary-gonadal (HPG) axis. It triggers the release of GnRH, which stimulates LH and FSH production, making it a powerful natural testosterone stimulator without suppression.

Follistatin-344 is a naturally occurring glycoprotein that binds and neutralizes myostatin and activin, two proteins that limit muscle growth. By inhibiting these muscle growth inhibitors, follistatin promotes significant muscle hypertrophy and strength gains. The 344 isoform is the most commonly studied.

DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide that modulates sleep architecture, promoting delta wave (deep) sleep. It also influences stress hormones, pain perception, and has shown antioxidant properties. Originally isolated from rabbit cerebral venous blood.

Snap-8 (Acetyl Octapeptide-3) is an anti-wrinkle peptide that works similarly to Botox but through topical application. It inhibits the SNARE complex formation needed for muscle contraction, reducing the depth of wrinkles caused by repeated facial expressions, particularly around the forehead and eyes.

Humanin is a 24-amino acid mitochondrial-derived peptide with potent cytoprotective and neuroprotective properties. It protects cells against Alzheimer-related toxicity, oxidative stress, and apoptosis. Discovered in 2001, it is one of the first identified mitochondrial-derived peptides (MDPs).

KPV is a naturally occurring anti-inflammatory tripeptide derived from alpha-melanocyte stimulating hormone (alpha-MSH). It exhibits potent anti-inflammatory effects by inhibiting NF-kB pathway activation. Studied for inflammatory bowel disease, skin inflammation, and wound healing.

Dihexa is a potent nootropic peptide derived from angiotensin IV. It is reported to be approximately 10 million times more potent than BDNF at promoting synaptic connectivity. It enhances cognitive function by driving new synapse formation through hepatocyte growth factor (HGF) pathway activation.

PEG-MGF is a pegylated form of Mechano Growth Factor, a splice variant of IGF-1 that is released in response to mechanical stress on muscle tissue. The PEG modification extends its half-life from minutes to hours. It activates satellite cells for muscle repair and hyperplasia.

MGF (Mechano Growth Factor) is a splice variant of IGF-1 produced in response to mechanical overload of skeletal muscle. It activates satellite cells to initiate muscle repair and new fiber formation. The native form has a very short half-life, which is why PEG-MGF was developed.

FOXO4-DRI is a cell-penetrating senolytic peptide that selectively targets and eliminates senescent (zombie) cells. It works by disrupting the interaction between FOXO4 and p53, causing senescent cells to undergo apoptosis while leaving healthy cells unaffected. A breakthrough in aging research.

Myostatin Propeptide is the natural inhibitor of myostatin (GDF-8), the protein that limits muscle growth. By binding to and neutralizing myostatin, the propeptide removes the biological brake on muscle development. Animals with myostatin mutations display extreme muscularity, validating this target.

PDA is an emerging healing peptide related to the BPC family. It shows promise in accelerating tissue repair and modulating inflammatory responses. Research focuses on its potential applications in musculoskeletal and gastrointestinal healing.

Adipotide is a peptidomimetic that targets and destroys the blood supply to fat tissue (adipose vasculature). It uses a homing sequence to find blood vessels feeding white fat cells and a proapoptotic sequence to destroy them. Studied for rapid, targeted fat loss in primate models.