IGF-1 DES
Des(1-3) Insulin-like Growth Factor 1
67 Amino Acids · MW: 7365 Da
Amino Acids
67
Molecular Weight
7365 Da
Half-life
~20-30 minutes
Research Score
74.0
Studies
65
Storage
-20°C lyophilized, 2-8°C reconstituted
What is IGF-1 DES?
IGF-1 DES is a truncated IGF-1 analog missing three N-terminal amino acids, making it approximately 10x more potent than regular IGF-1 because it does not bind to IGF binding proteins.
Key Benefits & Mechanisms
Highly potent localized muscle growth, enhanced protein synthesis, satellite cell proliferation, does not bind to IGFBPs, rapid onset
Research Summary
Missing first three amino acids (Gly-Pro-Glu) eliminates IGFBP binding, resulting in 100% bioavailable IGF-1R stimulation. Activates PI3K/Akt/mTOR for protein synthesis and satellite cell proliferation.
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