Kisspeptin-54
Kisspeptin-54 (metastin), 54-amino-acid KISS1 peptide fragment
54 Amino Acids · MW: 5.9 kDa
Amino Acids
54
Molecular Weight
5.9 kDa
Half-life
about 20-30 min
Research Score
5.0
Studies
110
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Kisspeptin-54?
Kisspeptin-54 is a real human peptide that activates the reproductive axis by stimulating GnRH release and downstream sex-hormone signaling. While it is not a direct erectile drug, it has meaningful literature around sexual behavior, arousal, and fertility-axis modulation.
Key Benefits & Mechanisms
GnRH/LH stimulation
supports sex hormone signaling
may enhance sexual motivation
fertility-axis modulation
Research Summary
Human studies show that kisspeptin-54 can acutely modulate reproductive neuroendocrine signaling, which makes it relevant to libido and sexual motivation research. Its effects are indirect compared with PT-141, but it is a well-established peptide in the scientific literature.
Related Peptides
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An endogenous KISS1-derived neuropeptide fragment that activates KISS1R and drives GnRH release upstream of LH and FSH secretion. It is studied as a translational tool for fertility and reproductive-axis physiology.
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