Leuprolide

Leuprolide acetate

9 Amino Acids · MW: 1209.39 Da

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Amino Acids

Molecular Weight

1209.39 Da

Half-life

~3 hours; depot lasts weeks

Research Score

4.8

Studies

1200

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is Leuprolide?

A widely used synthetic GnRH agonist that suppresses pituitary gonadotropins after an initial flare. In reproductive medicine it is used for cycle control, down-regulation, and hormone-sensitive gynecologic conditions.

Key Benefits & Mechanisms

pituitary suppression

cycle synchronization

ovarian stimulation timing

endometriosis-related reproductive care

Research Summary

Leuprolide is one of the best-studied GnRH analogs in reproductive medicine and assisted reproduction. It produces an initial flare followed by receptor desensitization and reduced LH/FSH output.

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