Kisspeptin-52
Kisspeptin-52 (KISS1-derived peptide fragment)
52 Amino Acids · MW: ≈5,800 Da
Amino Acids
52
Molecular Weight
≈5,800 Da
Half-life
Minutes to ~1 hour
Research Score
4.4
Studies
120
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Kisspeptin-52?
An endogenous KISS1-derived neuropeptide fragment that activates KISS1R and drives GnRH release upstream of LH and FSH secretion. It is studied as a translational tool for fertility and reproductive-axis physiology.
Key Benefits & Mechanisms
stimulates GnRH signaling
supports LH/FSH release
aids ovulation research
maps reproductive-axis function
Research Summary
Human and animal studies show kisspeptin-52 can acutely increase gonadotropin secretion and activate the hypothalamic-pituitary-gonadal axis. It has been explored in fertility research and assisted-reproduction settings as a way to trigger endogenous reproductive hormone release.
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