Atrial Natriuretic Peptide (ANP-28)
Human Atrial Natriuretic Peptide
SLRRSSCFGGRMDRIGAQSGLGCNSFRY Amino Acids · MW: ~3070 Da
Amino Acids
SLRRSSCFGGRMDRIGAQSGLGCNSFRY
Molecular Weight
~3070 Da
Half-life
2-5 min
Research Score
4.2
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Atrial Natriuretic Peptide (ANP-28)?
Endogenous cardiac hormone released mainly from atrial myocytes in response to stretch. It promotes natriuresis, diuresis, and vasodilation via NPR-A/guanylyl cyclase signaling.
Key Benefits & Mechanisms
natriuresis
vasodilation
cGMP elevation
Research Summary
Well-documented endogenous hormone central to blood-pressure and volume regulation; extensively studied as a biomarker and as a mechanistic probe for cGMP signaling.
Related Peptides
GLP-1(7-36) amide
Glucagon-like peptide-1 (7-36) amide
An endogenous incretin peptide released from intestinal L-cells after nutrient intake. It enhances glucose-dependent insulin secretion and slows gastric emptying, making it one of the most important gut hormones in metabolism research.
Endocrine PeptidesCholecystokinin-8
Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)
A bioactive fragment of cholecystokinin that is widely used to study GI hormone signaling. It stimulates gallbladder contraction and pancreatic enzyme secretion and is a major satiety-related gut peptide.
Endocrine PeptidesB-Type Natriuretic Peptide (BNP-32)
Human B-Type Natriuretic Peptide
Endogenous peptide hormone produced predominantly by ventricular myocardium under stretch/stress. It is a major clinical biomarker for heart failure and a potent activator of NPR-A/cGMP pathways.
Endocrine PeptidesC-Type Natriuretic Peptide (CNP-22)
Human C-Type Natriuretic Peptide
Endogenous natriuretic peptide expressed in the brain, vascular endothelium, and other tissues. It preferentially signals through NPR-B to raise cGMP and support vascular and skeletal biology.
Endocrine Peptides