Peptide Database

MK-677 is a potent oral growth hormone secretagogue that mimics ghrelin, producing sustained 24-hour elevations in GH and IGF-1 without suppressing natural production.

HGH Fragment 176-191 is the fat-reducing portion of the growth hormone molecule, shown to be 12.5x more potent than regular GH for fat loss while having no effect on blood sugar or cell proliferation.

Tesofensine is a triple monoamine reuptake inhibitor originally developed for neurological diseases, discovered to cause dramatic weight loss — averaging 12.8 kg in 6 months at therapeutic doses.

AICAR is an AMP-activated protein kinase (AMPK) agonist that mimics the metabolic effects of exercise, enhancing endurance, fat oxidation, and mitochondrial biogenesis without physical training.

IGF-1 DES is a truncated IGF-1 analog missing three N-terminal amino acids, making it approximately 10x more potent than regular IGF-1 because it does not bind to IGF binding proteins.

5-Amino-1MQ is a small molecule NNMT inhibitor that redirects cellular metabolism toward increased energy expenditure and reduced fat accumulation, representing a novel non-hormonal approach to weight management.

A 33-amino-acid neuropeptide involved in wakefulness, attention, and reward signaling. It is studied as a potential tool for boosting alertness and memory-related processing in experimental models.

Irisin is a cleavage product of FNDC5 that has been studied for exercise-linked improvements in glucose homeostasis and energy expenditure. It can influence AMPK, SIRT1, and PGC-1α signaling in metabolic tissues.

A Russian-developed actoprotector and adaptogenic stimulant with reported anti-fatigue and anxiolytic properties. It is commonly discussed in cognitive-enhancement contexts for motivation, resilience, and mental energy.

A synthetic research compound known for a small but notable human memory study. It is discussed as a short-acting nootropic with effects on recall and learning retention.

A bioactive fragment of cholecystokinin that is widely used to study GI hormone signaling. It stimulates gallbladder contraction and pancreatic enzyme secretion and is a major satiety-related gut peptide.

An endogenous incretin peptide released from intestinal L-cells after nutrient intake. It enhances glucose-dependent insulin secretion and slows gastric emptying, making it one of the most important gut hormones in metabolism research.

Synthetic tetrapeptide often discussed as a geroprotective and circadian-modulating peptide. Cognitive benefits are mostly indirect, via aging, sleep, and neuroprotection pathways.

A 20-amino-acid neuropeptide best known for its anxiolytic and arousal-modulating effects in preclinical studies. It is of interest for stress resilience, attention, and mood regulation, but it remains research-only.

A synthetic 14-amino-acid guanylate cyclase-C agonist used for chronic constipation and IBS-C. It increases intestinal fluid secretion and can improve stool frequency while indirectly shaping the luminal environment.

Desmopressin is a synthetic vasopressin analog with greater selectivity for V2 receptors and reduced pressor activity. It has been investigated in some cognitive and memory studies because vasopressin-pathway signaling can alter consolidation and retrieval.

Arginine vasopressin is a naturally occurring nonapeptide hormone that also has documented CNS effects on memory and social cognition. In research settings it has been studied for its potential to influence consolidation, recall, and arousal-linked learning.

Noopept is a peptide-derived cognitive enhancer used as a research compound and sold in some markets as a nootropic. It is studied for memory, attention, and neurotrophic signaling, especially in animal and limited human data.

Davunetide is an eight-amino-acid peptide, also known as NAP, derived from the ADNP protein. It has been studied for microtubule stabilization, neuroprotection, and potential effects on cognition in neurodegenerative and injury models.

Glycyl-L-prolyl-L-glutamic acid (GPE) is a tripeptide derived from IGF-1 processing that has been studied for neuroprotection and synaptic support. It has been explored in models of learning, memory retention, and injury-related cognitive decline.

A synthetic 16-amino-acid peptide and GC-C agonist related to uroguanylin. It is used to treat chronic idiopathic constipation and IBS-C by promoting intestinal secretion and softer stools.

A 51-amino-acid peptide hormone that strongly suppresses muscle protein breakdown and promotes glucose and amino acid uptake. In research and clinical settings it is primarily used for glycemic control, but it is also one of the most established anti-catabolic signals in skeletal muscle.

Kisspeptin-54 is a real human peptide that activates the reproductive axis by stimulating GnRH release and downstream sex-hormone signaling. While it is not a direct erectile drug, it has meaningful literature around sexual behavior, arousal, and fertility-axis modulation.

An endogenous 27-amino-acid peptide released from the duodenum in response to acidic chyme. It stimulates pancreatic bicarbonate secretion and supports digestion in the upper GI tract.