Secretin vs Cholecystokinin-8
Head-to-head comparison of Secretin (Human Secretin) and Cholecystokinin-8 (Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Secretin | Cholecystokinin-8 |
|---|---|---|
| Category | Gastrointestinal | Endocrine Peptides |
| Full Name | Human Secretin | Cholecystokinin (sulfated C-terminal octapeptide, CCK-8) |
| Molecular Weight | 3055.4 Da | 1143.2 Da |
| Half-Life | 5-7 minutes | 1-2 min |
| Amino Acids | 27 | DY(SO3H)MGWMDF-NH2 |
| Typical Dose | 0.2 mcg/kg IV | physiologic low-picomolar-nanomolar range|research-dependent |
| Route | Intravenous | endogenous secretion|research IV/SC |
| Purity | ≥98% | ≥98% |
| Studies Count | 800 | 97 |
| Research Status | Clinical | Endogenous |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
Cholecystokinin-8 Benefits
- ✓gallbladder contraction
- ✓pancreatic enzyme release
- ✓satiety signaling
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
Cholecystokinin-8 Dosing
physiologic secretion|research-dependent
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
Cholecystokinin-8 Side Effects
- ⚠abdominal cramping
- ⚠nausea
- ⚠biliary contraction
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
Cholecystokinin-8
CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.