Secretin vs Teduglutide
Head-to-head comparison of Secretin (Human Secretin) and Teduglutide (Teduglutide (glycyl-2 human glucagon-like peptide-2 analog)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Secretin | Teduglutide |
|---|---|---|
| Category | Gastrointestinal | Gastrointestinal |
| Full Name | Human Secretin | Teduglutide (glycyl-2 human glucagon-like peptide-2 analog) |
| Molecular Weight | 3055.4 Da | 3752 Da |
| Half-Life | 5-7 minutes | approximately 2-3 hours |
| Amino Acids | 27 | 33 |
| Typical Dose | 0.2 mcg/kg IV | 0.05 mg/kg/day |
| Route | Intravenous | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 800 | 300 |
| Research Status | Clinical | Clinical |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
Teduglutide Benefits
- ✓mucosal-growth
- ✓absorption-support
- ✓barrier-repair
- ✓intestinal-adaptation
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
Teduglutide Dosing
0.05 mg/kg once daily subcutaneous injection|chronic maintenance dosing in approved use|monitor fluid status and intestinal anatomy
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
Teduglutide Side Effects
- ⚠abdominal pain
- ⚠fluid retention
- ⚠polyp/neoplasia monitoring needed
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
Teduglutide
Teduglutide has robust clinical evidence showing improved intestinal absorption and reduced parenteral nutrition dependence in short bowel syndrome. Its mechanism, via GLP-2 receptor activation, makes it highly relevant to mucosal healing and intestinal adaptation research.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.