Home/Database/Teduglutide
GastrointestinalClinical

Teduglutide

Teduglutide (glycyl-2 human glucagon-like peptide-2 analog)

33 Amino Acids · MW: 3752 Da

Amino Acids

33

Molecular Weight

3752 Da

Half-life

approximately 2-3 hours

Research Score

4.8

Studies

300

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is Teduglutide?

Teduglutide is a GLP-2 analog that promotes intestinal growth, absorption, and mucosal repair. It is approved for short bowel syndrome and is one of the strongest peptide-based pro-restitution agents in gastrointestinal medicine.

Key Benefits & Mechanisms

mucosal-growth

absorption-support

barrier-repair

intestinal-adaptation

Research Summary

Teduglutide has robust clinical evidence showing improved intestinal absorption and reduced parenteral nutrition dependence in short bowel syndrome. Its mechanism, via GLP-2 receptor activation, makes it highly relevant to mucosal healing and intestinal adaptation research.