Substance P
Substance P
11 Amino Acids · MW: 1347.6 Da
Amino Acids
11
Molecular Weight
1347.6 Da
Half-life
minutes
Research Score
4.0
Studies
112
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Substance P?
Substance P is an undecapeptide tachykinin involved in neurogenic inflammation, pain signaling, and tissue repair signaling. In wound and muscle-injury models, it has been studied for effects on cell migration, vascular responses, and closure dynamics.
Key Benefits & Mechanisms
promotes fibroblast migration
supports angiogenesis
may accelerate wound closure
may aid tissue repair signaling
Research Summary
Research has examined Substance P as a mediator that can recruit repair-associated cells and influence local healing responses. It is most often discussed in wound healing and nerve-associated repair literature rather than as a standalone regenerative therapy.
Related Peptides
EGF
Human Epidermal Growth Factor
EGF is a small endogenous growth factor that drives epithelial cell migration and proliferation during tissue repair. It has been studied for burns, ulcers, and mucosal healing because it can accelerate re-epithelialization.
Recovery & HealingFGF2
Recombinant Human Fibroblast Growth Factor 2
FGF2 is a potent mitogen involved in angiogenesis, fibroblast expansion, and granulation tissue formation. It is widely studied in skin repair, ischemic tissue recovery, and chronic wound models.
Recovery & HealingrhPDGF-BB
Recombinant Human Platelet-Derived Growth Factor-BB
rhPDGF-BB is a dimeric growth factor that recruits fibroblasts and smooth muscle cells into the wound bed. It has a well-known role in chronic wound care, especially diabetic foot ulcers, where it supports granulation and closure.
Recovery & HealingPalifermin
Recombinant Human Keratinocyte Growth Factor (KGF, FGF7)
Palifermin is a truncated recombinant form of keratinocyte growth factor that protects and expands epithelial tissues. It is most recognized for mucosal protection, but the same biology is relevant to epithelial recovery and healing.
Recovery & Healing