Palifermin
Recombinant Human Keratinocyte Growth Factor (KGF, FGF7)
140 Amino Acids · MW: 16.3 kDa
Amino Acids
140
Molecular Weight
16.3 kDa
Half-life
4–6 hours
Research Score
4.3
Studies
250
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Palifermin?
Palifermin is a truncated recombinant form of keratinocyte growth factor that protects and expands epithelial tissues. It is most recognized for mucosal protection, but the same biology is relevant to epithelial recovery and healing.
Key Benefits & Mechanisms
epithelial protection
mucosal regeneration
barrier restoration
reduced inflammatory injury
Research Summary
Palifermin is clinically established for mucosal protection and has been studied for epithelial repair in other tissues. The strongest evidence is for epithelial resilience and regeneration rather than direct dermal remodeling.
Related Peptides
EGF
Human Epidermal Growth Factor
EGF is a small endogenous growth factor that drives epithelial cell migration and proliferation during tissue repair. It has been studied for burns, ulcers, and mucosal healing because it can accelerate re-epithelialization.
Recovery & HealingFGF2
Recombinant Human Fibroblast Growth Factor 2
FGF2 is a potent mitogen involved in angiogenesis, fibroblast expansion, and granulation tissue formation. It is widely studied in skin repair, ischemic tissue recovery, and chronic wound models.
Recovery & HealingrhPDGF-BB
Recombinant Human Platelet-Derived Growth Factor-BB
rhPDGF-BB is a dimeric growth factor that recruits fibroblasts and smooth muscle cells into the wound bed. It has a well-known role in chronic wound care, especially diabetic foot ulcers, where it supports granulation and closure.
Recovery & HealingAc-SDKP
N-Acetyl-Seryl-Aspartyl-Lysyl-Proline
Ac-SDKP is a naturally occurring tetrapeptide studied for tissue remodeling and repair signaling. It is best known for anti-fibrotic and pro-resolution effects that may support healthier healing responses.
Recovery & Healing