SNX-482
SNX-482 peptide from Hysterocrates gigas venom
41 Amino Acids · MW: 4,300 Da
Amino Acids
41
Molecular Weight
4,300 Da
Half-life
Minutes to hours
Research Score
4.3
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is SNX-482?
SNX-482 is a tarantula venom peptide that blocks Cav2.3 R-type calcium channels. It is used in electrophysiology and neurobiology as a selective ion-channel probe.
Key Benefits & Mechanisms
Cav2.3 blockade
synaptic transmission studies
excitability mapping
pain and epilepsy research
Research Summary
SNX-482 has been used to dissect R-type calcium currents in neurons and endocrine cells, and to map the role of Cav2.3 in excitability. Its selectivity profile has made it a standard research reagent in channel pharmacology.
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Experimental