BMP-2
Recombinant Human Bone Morphogenetic Protein-2
114 Amino Acids · MW: 26000 Da
Amino Acids
114
Molecular Weight
26000 Da
Half-life
short, localized exposure
Research Score
4.7
Studies
1500
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is BMP-2?
An osteoinductive growth factor used in orthopedic and dental regeneration to promote new bone formation. It is widely studied in scaffold-based repair and bone defect healing, with some work also exploring cartilage and joint applications.
Key Benefits & Mechanisms
promotes osteogenesis
supports nonunion healing
enhances scaffold-based repair
may improve defect fill
Research Summary
rhBMP-2 has strong clinical and translational literature for bone regeneration, spinal fusion, and defect repair. Its use is primarily local because systemic exposure is not the intended mechanism.
Related Peptides
EGF
Human Epidermal Growth Factor
EGF is a small endogenous growth factor that drives epithelial cell migration and proliferation during tissue repair. It has been studied for burns, ulcers, and mucosal healing because it can accelerate re-epithelialization.
Recovery & HealingFGF2
Recombinant Human Fibroblast Growth Factor 2
FGF2 is a potent mitogen involved in angiogenesis, fibroblast expansion, and granulation tissue formation. It is widely studied in skin repair, ischemic tissue recovery, and chronic wound models.
Recovery & HealingrhPDGF-BB
Recombinant Human Platelet-Derived Growth Factor-BB
rhPDGF-BB is a dimeric growth factor that recruits fibroblasts and smooth muscle cells into the wound bed. It has a well-known role in chronic wound care, especially diabetic foot ulcers, where it supports granulation and closure.
Recovery & HealingPalifermin
Recombinant Human Keratinocyte Growth Factor (KGF, FGF7)
Palifermin is a truncated recombinant form of keratinocyte growth factor that protects and expands epithelial tissues. It is most recognized for mucosal protection, but the same biology is relevant to epithelial recovery and healing.
Recovery & Healing