Plitidepsin
Dehydrodidemnin B (Plitidepsin)
N/A Amino Acids · MW: 1110.3 Da
Amino Acids
N/A
Molecular Weight
1110.3 Da
Half-life
Approximately 44 hours
Research Score
4.8
Studies
240
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Plitidepsin?
Plitidepsin is a cyclic depsipeptide originally isolated from the tunicate Aplidium albicans. It is a potent experimental anticancer compound and has also been investigated for antiviral activity.
Key Benefits & Mechanisms
antineoplastic
antiviral
pro-apoptotic
anti-inflammatory
Research Summary
Plitidepsin has been studied for its ability to disrupt eEF1A-dependent pathways, induce oxidative stress, and suppress tumor cell growth. It has reached clinical oncology development and was also evaluated as a candidate against SARS-CoV-2 in the literature.
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Experimental