Kahalalide F
Kahalalide F
N/A Amino Acids · MW: 1111.3 Da
Amino Acids
N/A
Molecular Weight
1111.3 Da
Half-life
N/A
Research Score
4.1
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Kahalalide F?
Kahalalide F is a marine cyclic depsipeptide associated with the sea slug Elysia rufescens and its algal diet. It attracted attention for activity against prostate cancer and other solid tumor models.
Key Benefits & Mechanisms
antineoplastic
pro-apoptotic
membrane-active
anti-proliferative
Research Summary
Kahalalide F was investigated in multiple preclinical and early clinical cancer studies because of its unusual membrane-disrupting and anti-tumor effects. Development highlighted the promise and limits of marine depsipeptides as oncology leads.
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Experimental