IDR-1018
IDR-1018 (Innate Defense Regulator peptide 1018; VRLIVAVRIWRR-NH2)
12 Amino Acids · MW: N/A
Amino Acids
12
Molecular Weight
N/A
Half-life
short; minutes to hours depending on formulation
Research Score
3.6
Studies
25
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is IDR-1018?
IDR-1018 is a synthetic host-defense peptide designed to tune immune signaling rather than act as a classic antibiotic. It has been studied for accelerating wound repair while reducing excessive inflammation in infected or inflammatory settings.
Key Benefits & Mechanisms
antimicrobial host-defense modulation
faster wound repair
reduced scar formation
inflammation control
Research Summary
IDR-1018 belongs to a class of immune-modulating peptides that can alter leukocyte behavior, inflammatory tone, and tissue repair outcomes. Preclinical literature shows interest in wound healing, biofilm-associated infection, and scar modulation.
Related Peptides
EGF
Human Epidermal Growth Factor
EGF is a small endogenous growth factor that drives epithelial cell migration and proliferation during tissue repair. It has been studied for burns, ulcers, and mucosal healing because it can accelerate re-epithelialization.
Recovery & HealingFGF2
Recombinant Human Fibroblast Growth Factor 2
FGF2 is a potent mitogen involved in angiogenesis, fibroblast expansion, and granulation tissue formation. It is widely studied in skin repair, ischemic tissue recovery, and chronic wound models.
Recovery & HealingrhPDGF-BB
Recombinant Human Platelet-Derived Growth Factor-BB
rhPDGF-BB is a dimeric growth factor that recruits fibroblasts and smooth muscle cells into the wound bed. It has a well-known role in chronic wound care, especially diabetic foot ulcers, where it supports granulation and closure.
Recovery & HealingPalifermin
Recombinant Human Keratinocyte Growth Factor (KGF, FGF7)
Palifermin is a truncated recombinant form of keratinocyte growth factor that protects and expands epithelial tissues. It is most recognized for mucosal protection, but the same biology is relevant to epithelial recovery and healing.
Recovery & Healing