Didemnin B
Didemnin B
N/A Amino Acids · MW: 1112.4 Da
Amino Acids
N/A
Molecular Weight
1112.4 Da
Half-life
N/A
Research Score
4.3
Studies
120
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Didemnin B?
Didemnin B is a marine cyclic depsipeptide first isolated from the tunicate Trididemnum solidum. It is one of the classic marine natural products that advanced into human studies because of strong antiproliferative activity.
Key Benefits & Mechanisms
antineoplastic
antiviral
pro-apoptotic
immunomodulatory
Research Summary
Didemnin B showed strong cytotoxic and antiviral activity in early literature and became an important scaffold for later marine drug development. Its clinical progress was limited by toxicity, but it remains highly cited as a foundational marine depsipeptide.
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Experimental