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Cibinetide

Cibinetide (ARA-290; erythropoietin-derived helix B surface peptide analogue)

11 Amino Acids · MW: 1211 Da

Amino Acids

11

Molecular Weight

1211 Da

Half-life

minutes to ~1 hour

Research Score

4.6

Studies

140

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is Cibinetide?

Cibinetide is a synthetic non-erythropoietic peptide derived from erythropoietin's tissue-protective signaling region. It is studied for anti-inflammatory and reparative effects without the hematocrit-raising activity of EPO.

Key Benefits & Mechanisms

tissue protection

anti-inflammatory signaling

microvascular support

nerve repair support

Research Summary

Cibinetide has been investigated as a tissue-protective EPO-mimetic that can modulate innate immune and repair pathways. Early studies have explored neuropathy, ischemia-reperfusion injury, and inflammatory tissue recovery.