BMP-12
Bone Morphogenetic Protein 12 (Growth Differentiation Factor 7)
120 (mature domain) Amino Acids · MW: 13000 Da
Amino Acids
120 (mature domain)
Molecular Weight
13000 Da
Half-life
hours to days in delivery systems
Research Score
4.4
Studies
88
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is BMP-12?
BMP-12, also known as GDF7, is a tendon-associated growth factor studied for tenogenic and ligament-like differentiation. It has been used in tendon and enthesis repair research, especially in scaffold and gene-delivery models.
Key Benefits & Mechanisms
promotes tenogenic signaling
supports collagen matrix formation
may improve enthesis healing
encourages tendon/ligament differentiation
Research Summary
BMP-12 is one of the better-known research factors for tendon and ligament regeneration work. Preclinical studies explore it as a way to drive tendon-like tissue formation rather than generic scar tissue.
Related Peptides
EGF
Human Epidermal Growth Factor
EGF is a small endogenous growth factor that drives epithelial cell migration and proliferation during tissue repair. It has been studied for burns, ulcers, and mucosal healing because it can accelerate re-epithelialization.
Recovery & HealingFGF2
Recombinant Human Fibroblast Growth Factor 2
FGF2 is a potent mitogen involved in angiogenesis, fibroblast expansion, and granulation tissue formation. It is widely studied in skin repair, ischemic tissue recovery, and chronic wound models.
Recovery & HealingrhPDGF-BB
Recombinant Human Platelet-Derived Growth Factor-BB
rhPDGF-BB is a dimeric growth factor that recruits fibroblasts and smooth muscle cells into the wound bed. It has a well-known role in chronic wound care, especially diabetic foot ulcers, where it supports granulation and closure.
Recovery & HealingPalifermin
Recombinant Human Keratinocyte Growth Factor (KGF, FGF7)
Palifermin is a truncated recombinant form of keratinocyte growth factor that protects and expands epithelial tissues. It is most recognized for mucosal protection, but the same biology is relevant to epithelial recovery and healing.
Recovery & Healing