Apratoxin A

N/A Amino Acids · MW: N/A

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Amino Acids

N/A

Molecular Weight

N/A

Half-life

N/A

Research Score

4.5

Studies

140

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is Apratoxin A?

Apratoxin A is a potent marine cyanobacterial cyclodepsipeptide originally associated with Lyngbya majuscula and related species. It is widely used as a research lead because it blocks protein translocation at Sec61 and shows strong anti-cancer activity.

Key Benefits & Mechanisms

antineoplastic

anti-angiogenic

Sec61 inhibition

anti-proliferative

Research Summary

Apratoxin A is a well-studied lead compound for targeting secretory and membrane protein biogenesis in cancer cells. Medicinal chemistry programs around apratoxins focus on improving selectivity and reducing hepatotoxicity while preserving potency.

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