GLP-1(7-36) amide vs hCG

Head-to-head comparison of GLP-1(7-36) amide (Glucagon-like peptide-1 (7-36) amide) and hCG (Human Chorionic Gonadotropin) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyGLP-1(7-36) amidehCG
CategoryEndocrine PeptidesSexual Health
Full NameGlucagon-like peptide-1 (7-36) amideHuman Chorionic Gonadotropin
Molecular Weight3297.7 Da36,700 Da
Half-Life1-2 min~24-36 hours
Amino AcidsHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2N/A
Typical DosepM-nM physiologic range|research-dependent500-2,000 IU per dose
Routeendogenous secretion|SC/IV in research/clinical analog studiesSubcutaneous/Intramuscular
Purity≥98%≥98%
Studies Count992000
Research StatusEndogenousClinical

GLP-1(7-36) amide Benefits

  • glucose-dependent insulin secretion
  • gastric emptying delay
  • satiety signaling

hCG Benefits

  • stimulates endogenous testosterone
  • supports spermatogenesis
  • preserves testicular volume
  • may improve fertility markers

GLP-1(7-36) amide Dosing

physiologic secretion|research-dependent

hCG Dosing

500-2,000 IU SC/IM 2-3x weekly|1,500-3,000 IU weekly in fertility protocols|titrate to testosterone, estradiol, and semen parameters

GLP-1(7-36) amide Side Effects

  • nausea
  • fullness
  • reduced appetite

hCG Side Effects

  • acne
  • gynecomastia
  • water retention

Research Overview

GLP-1(7-36) amide

One of the best-studied gut hormones, with strong evidence for incretin biology and appetite regulation. Native GLP-1 is rapidly degraded by DPP-4, which is why its biology is central to endocrine and metabolic pharmacology.

hCG

Human studies show hCG can raise intratesticular and serum testosterone by mimicking luteinizing hormone at the testis. It is commonly studied in male hypogonadism and fertility-preservation settings.

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Common Stacking Partners

GLP-1(7-36) amide stacks with:

L-cellsinsulinsatiety

hCG stacks with:

ClomipheneAnastrozole
gut-hormoneincretinendocrine-peptidegonadotropintestosteronefertilityclinical