hCG vs Cetrorelix
Head-to-head comparison of hCG (Human Chorionic Gonadotropin) and Cetrorelix (Cetrorelix acetate) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | hCG | Cetrorelix |
|---|---|---|
| Category | Sexual Health | Sexual Health |
| Full Name | Human Chorionic Gonadotropin | Cetrorelix acetate |
| Molecular Weight | 36,700 Da | 1431.06 Da |
| Half-Life | ~24-36 hours | ~30 hours |
| Amino Acids | N/A | 10 |
| Typical Dose | 500-2,000 IU per dose | 0.25 mg SC daily |
| Route | Subcutaneous/Intramuscular | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 2000 | 300 |
| Research Status | Clinical | Clinical |
hCG Benefits
- ✓stimulates endogenous testosterone
- ✓supports spermatogenesis
- ✓preserves testicular volume
- ✓may improve fertility markers
Cetrorelix Benefits
- ✓prevents premature ovulation
- ✓supports IVF cycle control
- ✓blocks LH surge
- ✓short-acting pituitary suppression
hCG Dosing
500-2,000 IU SC/IM 2-3x weekly|1,500-3,000 IU weekly in fertility protocols|titrate to testosterone, estradiol, and semen parameters
Cetrorelix Dosing
0.25 mg SC daily|start on stimulation day 5-6|protocol-dependent antagonist cycle
hCG Side Effects
- ⚠acne
- ⚠gynecomastia
- ⚠water retention
Cetrorelix Side Effects
- ⚠injection-site reactions
- ⚠headache
- ⚠nausea
Research Overview
hCG
Human studies show hCG can raise intratesticular and serum testosterone by mimicking luteinizing hormone at the testis. It is commonly studied in male hypogonadism and fertility-preservation settings.
Cetrorelix
Cetrorelix is a cornerstone GnRH antagonist in assisted reproduction, with a fast onset and reversible suppression of LH. Trials show it improves cycle management by reducing premature ovulation during stimulation.
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