RFRP-3
RFamide-Related Peptide-3
N/A Amino Acids · MW: N/A
Amino Acids
N/A
Molecular Weight
N/A
Half-life
Minutes
Research Score
3.6
Studies
140
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is RFRP-3?
A gonadotropin-inhibitory peptide that suppresses reproductive hormone signaling in many mammalian models. It is studied as a counter-regulator of the testosterone axis and a tool for mapping hormonal feedback loops.
Key Benefits & Mechanisms
maps negative feedback on reproduction
useful in endocrine mechanistic studies
may help model low-LH states
research tool for hormone regulation
Research Summary
Animal and translational studies show RFRP-3 can inhibit GnRH/LH signaling, indirectly reducing testicular testosterone output. It is frequently used to study reproductive inhibition, seasonal breeding, and stress-related endocrine changes.
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