Palmitoyl Tripeptide-5
Palmitoyl Tripeptide-5
3 Amino Acids · MW: 802 Da
Amino Acids
3
Molecular Weight
802 Da
Half-life
Short; likely hours in topical use
Research Score
3.9
Studies
12
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Palmitoyl Tripeptide-5?
A skin peptide designed for anti-aging and firmness-focused formulations. It is studied for collagen-supportive signaling and for helping improve the appearance of photoaged skin.
Key Benefits & Mechanisms
collagen support
firmness support
photoaging mitigation
dermal matrix support
Research Summary
Preclinical studies suggest it may influence TGF-beta-like pathways and promote collagen synthesis. Independent human evidence is limited, but it is used in collagen-focused cosmetic formulations.
Related Peptides
Rapamycin
Rapamycin (Sirolimus)
Rapamycin is a macrolide originally developed as an immunosuppressant and is one of the most studied geroscience compounds. In aging research, it is best known for inhibiting mTOR, a pathway strongly linked to nutrient sensing, autophagy, and lifespan regulation.
Anti-AgingMetformin
Metformin Hydrochloride
Metformin is a biguanide widely used for type 2 diabetes and heavily studied for geroprotection. Its anti-aging interest comes from effects on AMPK signaling, insulin sensitivity, inflammation, and cellular stress responses.
Anti-AgingNMN
Nicotinamide Mononucleotide
Nicotinamide mononucleotide is a direct NAD+ precursor studied for age-associated declines in cellular energy and repair processes. It is commonly researched in the context of mitochondrial function, DNA repair support, and metabolic resilience.
Anti-AgingSpermidine
Spermidine
Spermidine is a naturally occurring polyamine found in cells and foods such as wheat germ and soy. It is studied for its ability to promote autophagy and support cellular maintenance pathways that decline with age.
Anti-Aging