NR
Nicotinamide Riboside Chloride
N/A Amino Acids · MW: 290.69 Da
Amino Acids
N/A
Molecular Weight
290.69 Da
Half-life
1-3 hours
Research Score
4.7
Studies
250
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is NR?
Nicotinamide riboside is a vitamin B3 derivative used to raise NAD+ levels. It is studied for mitochondrial energy metabolism, DNA repair support, and age-related metabolic health.
Key Benefits & Mechanisms
boosts NAD+ levels
supports DNA repair
supports mitochondrial energy metabolism
may improve insulin sensitivity
Research Summary
NR has substantial human and animal research showing reliable NAD+ elevation after oral dosing. Clinical outcomes are still being defined, but it is one of the better-studied longevity-related compounds.
Related Peptides
Rapamycin
Rapamycin (Sirolimus)
Rapamycin is a macrolide originally developed as an immunosuppressant and is one of the most studied geroscience compounds. In aging research, it is best known for inhibiting mTOR, a pathway strongly linked to nutrient sensing, autophagy, and lifespan regulation.
Anti-AgingMetformin
Metformin Hydrochloride
Metformin is a biguanide widely used for type 2 diabetes and heavily studied for geroprotection. Its anti-aging interest comes from effects on AMPK signaling, insulin sensitivity, inflammation, and cellular stress responses.
Anti-AgingNMN
Nicotinamide Mononucleotide
Nicotinamide mononucleotide is a direct NAD+ precursor studied for age-associated declines in cellular energy and repair processes. It is commonly researched in the context of mitochondrial function, DNA repair support, and metabolic resilience.
Anti-AgingSpermidine
Spermidine
Spermidine is a naturally occurring polyamine found in cells and foods such as wheat germ and soy. It is studied for its ability to promote autophagy and support cellular maintenance pathways that decline with age.
Anti-Aging