Mesotocin
Mesotocin (oxytocin homolog)
9 Amino Acids · MW: 1007.19 Da
Amino Acids
9
Molecular Weight
1007.19 Da
Half-life
N/A; species-dependent
Research Score
3.9
Studies
220
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Mesotocin?
A naturally occurring oxytocin-like nonapeptide found across many non-mammalian vertebrates. It is a standard comparative endocrinology tool for studying social behavior, reproduction, and ancestral neurohypophyseal signaling.
Key Benefits & Mechanisms
comparative neuroendocrinology
reproductive signaling
social behavior research
uterotonic activity
Research Summary
Mesotocin is used heavily in animal neuroendocrine research to understand the evolution of oxytocin-like systems. It is often studied alongside isotocin and vasotocin to map receptor selectivity and behavioral effects across species.
Related Peptides
Carbetocin
1-deamino-1-monocarba-2-O-methyltyrosine oxytocin
A long-acting oxytocin analog engineered to resist rapid enzymatic degradation while preserving oxytocin receptor agonism. It is widely used and studied for postpartum hemorrhage prevention because of its prolonged uterotonic effect.
HormonalAtosiban
Atosiban (synthetic oxytocin receptor antagonist)
A synthetic peptide antagonist of the oxytocin receptor with vasopressin cross-reactivity at higher concentrations. It is a key compound for tocolysis and for probing oxytocin receptor signaling in reproductive biology.
HormonalTerlipressin
Triglycyl-lysine vasopressin
A synthetic vasopressin prodrug that is enzymatically converted to lysine vasopressin in vivo. It is used in portal hypertension and hepatorenal syndrome because of its potent vasoconstrictive profile.
HormonalCRH
Corticotropin-Releasing Hormone
Hypothalamic peptide that drives pituitary ACTH release and activates the stress axis. It is widely used in research to model cortisol and HPA-axis responses.
Hormonal