Endothelin-3
Human Endothelin-3
21 Amino Acids · MW: ~2,493 Da
Amino Acids
21
Molecular Weight
~2,493 Da
Half-life
~minutes
Research Score
3.9
Studies
180
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Endothelin-3?
A 21-amino-acid endothelial peptide that activates endothelin receptors and regulates vascular tone and neural crest biology. It is studied in vasoconstriction, endothelial signaling, and developmental biology.
Key Benefits & Mechanisms
vascular receptor research
endothelial signaling
smooth-muscle contractility
developmental biology
Research Summary
Endothelin-3 is less potent than endothelin-1 in many vascular beds but remains important in receptor biology and vascular signaling research. It is used to probe ET receptor subtype function, smooth-muscle responses, and endothelial cross-talk.
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