Cenderitide
CD-NP chimeric natriuretic peptide
37 Amino Acids · MW: ≈4,300 Da
Amino Acids
37
Molecular Weight
≈4,300 Da
Half-life
≈10–20 minutes
Research Score
4.0
Studies
35
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Cenderitide?
Cenderitide is a designer natriuretic peptide combining features of CNP and dendroaspis natriuretic peptide. It was engineered to provide balanced natriuretic and vasodilatory activity with potential renal-sparing effects.
Key Benefits & Mechanisms
natriuresis
vasodilation
renal protection
anti-fibrotic signaling
Research Summary
CD-NP has been explored in preclinical heart failure and chronic kidney disease models. The peptide showed favorable cGMP activation and natriuretic effects, supporting further translational work.
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