Dasatinib
Dasatinib
N/A Amino Acids · MW: 488.01 Da
Amino Acids
N/A
Molecular Weight
488.01 Da
Half-life
3-5 hours
Research Score
4.6
Studies
250
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Dasatinib?
Dasatinib is a clinically approved tyrosine kinase inhibitor that has become one of the best-known senolytic research compounds. In aging biology, it is studied for its ability to selectively weaken survival pathways in senescent cells.
Key Benefits & Mechanisms
senescent cell clearance
SASP reduction
tissue function support
pro-aging pathway suppression
Research Summary
Dasatinib has extensive preclinical literature as a senolytic, especially in intermittent regimens designed to avoid continuous toxicity. Studies suggest it can reduce senescent cell burden and improve age-related phenotypes in selected tissues and disease models.
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