Curcumin
Curcumin
N/A Amino Acids · MW: 368.38 Da
Amino Acids
N/A
Molecular Weight
368.38 Da
Half-life
1-2 hours
Research Score
4.6
Studies
3000
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Curcumin?
The principal curcuminoid from turmeric, widely studied for anti-inflammatory and antioxidant effects. In longevity literature it is often linked to SIRT1, AMPK, and stress-response signaling rather than direct NAD+ boosting.
Key Benefits & Mechanisms
modulates SIRT1/AMPK pathways
reduces oxidative stress
supports inflammatory balance
mitochondrial support
Research Summary
Curcumin modulates SIRT1, AMPK, and Nrf2-related stress responses in cell and animal models and is widely studied in aging-related inflammation. Human trials support some metabolic and inflammatory benefits, but bioavailability remains a major limitation.
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