Berberine
Berberine Chloride
N/A Amino Acids · MW: 371.81 Da
Amino Acids
N/A
Molecular Weight
371.81 Da
Half-life
4-6 hours
Research Score
4.4
Studies
1400
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Berberine?
An isoquinoline alkaloid known for metabolic benefits and broad research in glucose and lipid regulation. It is commonly placed in anti-aging discussions because it activates AMPK and can influence downstream SIRT1-related signaling.
Key Benefits & Mechanisms
activates AMPK
supports NAD+/SIRT1 signaling
improves metabolic aging markers
supports mitochondrial health
Research Summary
Berberine activates AMPK and has downstream effects on SIRT1, mitochondrial biogenesis, and glucose metabolism in preclinical models. Its human literature is substantial for metabolic health, making it a common longevity-oriented research compound.
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