Adrenomedullin
Human Adrenomedullin (AM)
52 Amino Acids · MW: ~6,050 Da
Amino Acids
52
Molecular Weight
~6,050 Da
Half-life
~20–30 min
Research Score
4.8
Studies
600
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Adrenomedullin?
Endogenous 52-amino-acid vasodilatory peptide produced by endothelial and vascular smooth muscle cells. It promotes nitric oxide release, increases cAMP signaling, and supports vascular homeostasis.
Key Benefits & Mechanisms
vasodilation
endothelial protection
natriuresis
afterload reduction
Research Summary
Adrenomedullin has been widely studied as a regulator of vascular tone, renal blood flow, and endothelial function. Human and animal studies suggest potential utility in hypertension, heart failure, pulmonary hypertension, and sepsis-related circulatory dysfunction.
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