Secretin vs C-peptide
Head-to-head comparison of Secretin (Human Secretin) and C-peptide (Connecting peptide (C-peptide)) — benefits, dosing, side effects, research data, and where to buy.
| Property | Secretin | C-peptide |
|---|---|---|
| Category | Gastrointestinal | Pain Management |
| Full Name | Human Secretin | Connecting peptide (C-peptide) |
| Molecular Weight | 3055.4 Da | 3020.3 Da |
| Half-Life | 5-7 minutes | ~20-30 min |
| Amino Acids | 27 | 31 |
| Typical Dose | 0.2 mcg/kg IV | no approved analgesic dose|research-only |
| Route | Intravenous | IV|subQ |
| Purity | ≥98% | ≥98% |
| Studies Count | 800 | 46 |
| Research Status | Clinical | Pre-clinical |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
C-peptide Benefits
- ✓diabetic neuropathy research
- ✓nerve function support
- ✓possible analgesic effect
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
C-peptide Dosing
0.5-1.0 mg/day in research|route varies by protocol
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
C-peptide Side Effects
- ⚠injection-site reactions
- ⚠unknown long-term safety
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
C-peptide
C-peptide is not an approved analgesic, but multiple studies have examined its effects on peripheral nerve blood flow and neuropathy outcomes. The strongest relevance is in diabetic neuropathic pain rather than migraine.
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