GLP-1(7-36) amide vs Glucagon
Head-to-head comparison of GLP-1(7-36) amide (Glucagon-like peptide-1 (7-36) amide) and Glucagon (Glucagon) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | GLP-1(7-36) amide | Glucagon |
|---|---|---|
| Category | Endocrine Peptides | Diabetes & Metabolic |
| Full Name | Glucagon-like peptide-1 (7-36) amide | Glucagon |
| Molecular Weight | 3297.7 Da | 3482.75 |
| Half-Life | 1-2 min | 5-10 min |
| Amino Acids | HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 | 29 |
| Typical Dose | pM-nM physiologic range|research-dependent | 1 mg IM/SC for severe hypoglycemia or 3 mg intranasal |
| Route | endogenous secretion|SC/IV in research/clinical analog studies | IM|SC|IN|IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 99 | 93 |
| Research Status | Endogenous | Approved |
GLP-1(7-36) amide Benefits
- ✓glucose-dependent insulin secretion
- ✓gastric emptying delay
- ✓satiety signaling
Glucagon Benefits
- ✓rapid hypoglycemia reversal
- ✓raises plasma glucose
- ✓useful in emergency rescue
GLP-1(7-36) amide Dosing
physiologic secretion|research-dependent
Glucagon Dosing
1 mg IM/SC|3 mg intranasal
GLP-1(7-36) amide Side Effects
- ⚠nausea
- ⚠fullness
- ⚠reduced appetite
Glucagon Side Effects
- ⚠nausea
- ⚠vomiting
Research Overview
GLP-1(7-36) amide
One of the best-studied gut hormones, with strong evidence for incretin biology and appetite regulation. Native GLP-1 is rapidly degraded by DPP-4, which is why its biology is central to endocrine and metabolic pharmacology.
Glucagon
Clinical and emergency medicine use is well established for severe hypoglycemia, with newer stable formulations improving ease of administration.
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Common Stacking Partners
GLP-1(7-36) amide stacks with:
L-cellsinsulinsatiety
Glucagon stacks with:
glucagonGlucaGenBaqsimiGvoke
gut-hormoneincretinendocrine-peptidediabetesmetabolicrescueglucose-regulation