GLP-1(7-36) amide vs Anamorelin

Head-to-head comparison of GLP-1(7-36) amide (Glucagon-like peptide-1 (7-36) amide) and Anamorelin (Anamorelin hydrochloride (ONO-7643)) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyGLP-1(7-36) amideAnamorelin
CategoryEndocrine PeptidesGrowth Hormone
Full NameGlucagon-like peptide-1 (7-36) amideAnamorelin hydrochloride (ONO-7643)
Molecular Weight3297.7 DaN/A
Half-Life1-2 minabout 9 hours
Amino AcidsHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2N/A
Typical DosepM-nM physiologic range|research-dependent50 mg/day
Routeendogenous secretion|SC/IV in research/clinical analog studiesOral
Purity≥98%≥98%
Studies Count9995
Research StatusEndogenousClinical

GLP-1(7-36) amide Benefits

  • glucose-dependent insulin secretion
  • gastric emptying delay
  • satiety signaling

Anamorelin Benefits

  • stimulates appetite
  • raises IGF-1
  • may support weight gain
  • oral dosing

GLP-1(7-36) amide Dosing

physiologic secretion|research-dependent

Anamorelin Dosing

50 mg orally once daily|often studied with food or per protocol|track weight, appetite, and glucose markers

GLP-1(7-36) amide Side Effects

  • nausea
  • fullness
  • reduced appetite

Anamorelin Side Effects

  • hyperglycemia
  • peripheral edema
  • constipation or nausea

Research Overview

GLP-1(7-36) amide

One of the best-studied gut hormones, with strong evidence for incretin biology and appetite regulation. Native GLP-1 is rapidly degraded by DPP-4, which is why its biology is central to endocrine and metabolic pharmacology.

Anamorelin

Trials in cachexia populations showed increased appetite and modest gains in body weight and IGF-1. Regulatory progress has varied by region, but it remains a well-studied ghrelin agonist in the GH space.

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Common Stacking Partners

GLP-1(7-36) amide stacks with:

L-cellsinsulinsatiety

Anamorelin stacks with:

Nutritional supportResistance training
gut-hormoneincretinendocrine-peptideghrelin-agonistcachexiagh-secretagogue