FGF2 vs Ac-SDKP
Head-to-head comparison of FGF2 (Recombinant Human Fibroblast Growth Factor 2) and Ac-SDKP (N-Acetyl-Seryl-Aspartyl-Lysyl-Proline) — benefits, dosing, side effects, research data, and where to buy.
| Property | FGF2 | Ac-SDKP |
|---|---|---|
| Category | Recovery & Healing | Recovery & Healing |
| Full Name | Recombinant Human Fibroblast Growth Factor 2 | N-Acetyl-Seryl-Aspartyl-Lysyl-Proline |
| Molecular Weight | 17.2 kDa | 432.4 Da |
| Half-Life | minutes to <1 hour local | minutes |
| Amino Acids | 155 | 4 |
| Typical Dose | 1–10 µg/cm²/day | 10–100 µg/kg/day in pre-clinical studies |
| Route | Topical | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 1200 | 180 |
| Research Status | Clinical | Pre-clinical |
FGF2 Benefits
- ✓angiogenesis
- ✓fibroblast proliferation
- ✓granulation tissue formation
- ✓accelerated re-epithelialization
Ac-SDKP Benefits
- ✓anti-inflammatory tissue remodeling
- ✓fibroblast modulation
- ✓microvascular protection
- ✓faster regenerative signaling
FGF2 Dosing
Topical spray/gel daily|intralesional microdoses in studies|short cycles during active repair
Ac-SDKP Dosing
Research-only systemic microdoses|short daily dosing in animal models|route varies by study
FGF2 Side Effects
- ⚠local swelling
- ⚠pain
- ⚠fibroblast overgrowth/scarring
- ⚠theoretical malignancy concern
Ac-SDKP Side Effects
- ⚠GI upset
- ⚠hypotension at high exposure
- ⚠unknown long-term safety
Research Overview
FGF2
FGF2 has extensive preclinical and clinical literature for skin ulcers, burns, and postsurgical repair, largely through angiogenic and mesenchymal-cell signaling. It remains one of the most studied repair factors for improving tissue perfusion and remodeling.
Ac-SDKP
Ac-SDKP has literature in tissue remodeling, angiogenesis, and organ repair models. Its strongest evidence is pre-clinical, where it modulates inflammation and fibrosis during healing.
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