Ac-SDKP vs BMP-7
Head-to-head comparison of Ac-SDKP (N-Acetyl-Seryl-Aspartyl-Lysyl-Proline) and BMP-7 (Recombinant Human Bone Morphogenetic Protein-7) — benefits, dosing, side effects, research data, and where to buy.
| Property | Ac-SDKP | BMP-7 |
|---|---|---|
| Category | Recovery & Healing | Recovery & Healing |
| Full Name | N-Acetyl-Seryl-Aspartyl-Lysyl-Proline | Recombinant Human Bone Morphogenetic Protein-7 |
| Molecular Weight | 432.4 Da | 35000 Da |
| Half-Life | minutes | short, localized exposure |
| Amino Acids | 4 | 139 |
| Typical Dose | 10–100 µg/kg/day in pre-clinical studies | procedure-dependent local implant |
| Route | Subcutaneous | Local/Implant |
| Purity | ≥98% | ≥98% |
| Studies Count | 180 | 700 |
| Research Status | Pre-clinical | Clinical |
Ac-SDKP Benefits
- ✓anti-inflammatory tissue remodeling
- ✓fibroblast modulation
- ✓microvascular protection
- ✓faster regenerative signaling
BMP-7 Benefits
- ✓supports bone formation
- ✓may aid nonunion repair
- ✓promotes connective tissue regeneration
- ✓helps scaffold integration
Ac-SDKP Dosing
Research-only systemic microdoses|short daily dosing in animal models|route varies by study
BMP-7 Dosing
local implantation|single procedural exposure|research or device-specific delivery
Ac-SDKP Side Effects
- ⚠GI upset
- ⚠hypotension at high exposure
- ⚠unknown long-term safety
BMP-7 Side Effects
- ⚠local swelling
- ⚠inflammation
- ⚠ectopic mineralization
Research Overview
Ac-SDKP
Ac-SDKP has literature in tissue remodeling, angiogenesis, and organ repair models. Its strongest evidence is pre-clinical, where it modulates inflammation and fibrosis during healing.
BMP-7
rhBMP-7 has a long history in preclinical and clinical literature for bone repair, particularly in challenging healing environments. Its cartilage-related research is less mature than BMP-2 but still relevant to musculoskeletal regeneration.
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