Cholecystokinin-8 vs hGHRH(1-44)
Head-to-head comparison of Cholecystokinin-8 (Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)) and hGHRH(1-44) (Human growth hormone-releasing hormone (1-44) amide) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Cholecystokinin-8 | hGHRH(1-44) |
|---|---|---|
| Category | Endocrine Peptides | Growth Hormone |
| Full Name | Cholecystokinin (sulfated C-terminal octapeptide, CCK-8) | Human growth hormone-releasing hormone (1-44) amide |
| Molecular Weight | 1143.2 Da | N/A |
| Half-Life | 1-2 min | 5-15 minutes |
| Amino Acids | DY(SO3H)MGWMDF-NH2 | 44 |
| Typical Dose | physiologic low-picomolar-nanomolar range|research-dependent | 0.1-1 mcg/kg |
| Route | endogenous secretion|research IV/SC | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 97 | 120 |
| Research Status | Endogenous | Clinical Research |
Cholecystokinin-8 Benefits
- ✓gallbladder contraction
- ✓pancreatic enzyme release
- ✓satiety signaling
hGHRH(1-44) Benefits
- ✓physiologic GH pulse support
- ✓IGF-1 pathway stimulation
- ✓pituitary receptor mapping
- ✓endocrine research tool
Cholecystokinin-8 Dosing
physiologic secretion|research-dependent
hGHRH(1-44) Dosing
0.1-1 mcg/kg SC or IV bolus for stimulation studies|single-dose endocrine challenge with timed GH sampling|pulsatile administration in clamp/infusion experiments
Cholecystokinin-8 Side Effects
- ⚠abdominal cramping
- ⚠nausea
- ⚠biliary contraction
hGHRH(1-44) Side Effects
- ⚠flushing
- ⚠headache
- ⚠transient nausea
Research Overview
Cholecystokinin-8
CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.
hGHRH(1-44)
Human GHRH(1-44) amide has been used extensively to characterize hypothalamic control of pituitary somatotrophs and the downstream GH/IGF-1 axis. It remains a standard comparator in studies of GHRH agonism, secretion dynamics, and receptor pharmacology.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.