Cholecystokinin-8 vs hGHRH(1-37)OH
Head-to-head comparison of Cholecystokinin-8 (Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)) and hGHRH(1-37)OH (Human growth hormone-releasing factor (1-37) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Cholecystokinin-8 | hGHRH(1-37)OH |
|---|---|---|
| Category | Endocrine Peptides | Growth Hormone |
| Full Name | Cholecystokinin (sulfated C-terminal octapeptide, CCK-8) | Human growth hormone-releasing factor (1-37) hydroxyl |
| Molecular Weight | 1143.2 Da | N/A |
| Half-Life | 1-2 min | 5-20 minutes |
| Amino Acids | DY(SO3H)MGWMDF-NH2 | 37 |
| Typical Dose | physiologic low-picomolar-nanomolar range|research-dependent | 1-2 mcg/kg |
| Route | endogenous secretion|research IV/SC | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 97 | 60 |
| Research Status | Endogenous | Clinical Research |
Cholecystokinin-8 Benefits
- ✓gallbladder contraction
- ✓pancreatic enzyme release
- ✓satiety signaling
hGHRH(1-37)OH Benefits
- ✓GH release studies
- ✓minimal-sequence mapping
- ✓receptor pharmacology
- ✓peptide stability research
Cholecystokinin-8 Dosing
physiologic secretion|research-dependent
hGHRH(1-37)OH Dosing
1-2 mcg/kg SC or IV bolus|acute stimulation with serial GH assays|short-course research administration with biomarker monitoring
Cholecystokinin-8 Side Effects
- ⚠abdominal cramping
- ⚠nausea
- ⚠biliary contraction
hGHRH(1-37)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠transient fatigue
Research Overview
Cholecystokinin-8
CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.
hGHRH(1-37)OH
Human GHRF(1-37)OH has appeared in studies examining how loss of C-terminal residues affects biological activity at the GHRH receptor. It is often used alongside other fragments to define structure-activity relationships within the GHRH family.
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