Arenicin-1 vs DPDPE
Head-to-head comparison of Arenicin-1 (Arenicin-1) and DPDPE ([D-Pen2, D-Pen5]-enkephalin) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Arenicin-1 | DPDPE |
|---|---|---|
| Category | Marine-Derived | Pain Management |
| Full Name | Arenicin-1 | [D-Pen2, D-Pen5]-enkephalin |
| Molecular Weight | 2079 Da | 645.79 Da |
| Half-Life | n/a | 15-60 minutes in plasma |
| Amino Acids | 21 | 5 |
| Typical Dose | n/a | 0.01-1 ug per animal |
| Route | preclinical | Intrathecal / intracerebroventricular |
| Purity | ≥98% | ≥98% |
| Studies Count | 76 | 800 |
| Research Status | Pre-clinical | Pre-clinical |
Arenicin-1 Benefits
- ✓antimicrobial
- ✓anti-biofilm
- ✓membrane-active
DPDPE Benefits
- ✓delta-opioid selectivity
- ✓improved conformational stability
- ✓analgesic receptor mapping
- ✓useful in chronic pain models
Arenicin-1 Dosing
bacterial infection|biofilm disruption
DPDPE Dosing
Intrathecal 0.01-1 ug per animal|Intracerebroventricular 0.01-0.5 ug per animal|In vitro 0.1-20 nM
Arenicin-1 Side Effects
- ⚠Arenicola marina
DPDPE Side Effects
- ⚠sedation
- ⚠nausea-like opioid effects
- ⚠tolerance with repeated dosing
Research Overview
Arenicin-1
Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.
DPDPE
DPDPE is widely cited in opioid pharmacology because it helped establish the functional role of delta-opioid receptors in pain control. Its constrained structure is also used to explore how peptide cyclization changes potency, stability, and tissue selectivity.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.