Variegin
Variegin, a tick-derived thrombin inhibitor peptide from Amblyomma variegatum
Amino Acids
N/A
Molecular Weight
N/A
Half-life
N/A
Research Score
4.3
Studies
87
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Variegin?
Variegin is a potent natural anticoagulant peptide that binds thrombin and suppresses clotting activity. It is studied as a template for next-generation antithrombotic agents.
Key Benefits & Mechanisms
b1
Research Summary
Research
Related Peptides
Hirudin
Hirudin, a natural 65-amino-acid direct thrombin inhibitor from the medicinal leech
Hirudin binds thrombin with very high affinity and blocks fibrin formation. It is a classic anticoagulant scaffold used to guide later antithrombotic peptide design.
AnticoagulantBivalirudin
Bivalirudin, a synthetic 20-amino-acid hirudin-derived direct thrombin inhibitor
Bivalirudin inhibits both the active site and exosite I of thrombin, reducing clot formation. It is widely known as a peptide anticoagulant used in cardiovascular intervention research and practice.
AnticoagulantLepirudin
Lepirudin, a recombinant desulfatohirudin direct thrombin inhibitor
Lepirudin is a recombinant hirudin analog that binds thrombin tightly and prevents fibrin clotting. It is one of the best-known peptide anticoagulants derived from the hirudin family.
AnticoagulantDesirudin
Desirudin, a recombinant hirudin variant used as a direct thrombin inhibitor
Desirudin blocks thrombin-mediated conversion of fibrinogen to fibrin and is a well-established hirudin-derived anticoagulant peptide. It is closely related to the natural leech peptide but optimized for therapeutic use.
Anticoagulant