Tachyplesin I
Tachyplesin I
17 Amino Acids · MW: 2394.8 Da
Amino Acids
17
Molecular Weight
2394.8 Da
Half-life
unknown; relatively protease-resistant in vitro
Research Score
4.1
Studies
84
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Tachyplesin I?
Tachyplesin I is a disulfide-stabilized antimicrobial peptide from the horseshoe crab Tachypleus tridentatus. It is strongly cationic and disrupts microbial membranes with high potency.
Key Benefits & Mechanisms
potent membrane-active antibacterial peptide
fungal activity
template for stable AMP design
Research Summary
Tachyplesin I has strong in vitro activity against Gram-positive and Gram-negative bacteria and has been studied as a stable scaffold for peptide engineering. Its disulfide-bonded structure makes it an interesting model for developing protease-resistant AMPs.
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