Magainin 2
Magainin-2
23 Amino Acids · MW: 2466.1 Da
Amino Acids
23
Molecular Weight
2466.1 Da
Half-life
minutes in serum
Research Score
4.0
Studies
82
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Magainin 2?
Magainin 2 is an amphibian antimicrobial peptide originally isolated from Xenopus laevis skin. It kills microbes mainly by disrupting membranes and is a classic model peptide for AMPs.
Key Benefits & Mechanisms
membrane-active antibacterial peptide
prototype AMP research tool
antibiofilm potential
Research Summary
Magainin 2 helped establish the membrane-disruption paradigm for antimicrobial peptides. It has strong in vitro antibacterial activity and remains important in research on peptide-based anti-infectives, though it is not an approved antibiotic.
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