Pro-Gly-Pro
L-Prolyl-glycyl-L-proline
Pro-Gly-Pro Amino Acids · MW: 269.30
Amino Acids
Pro-Gly-Pro
Molecular Weight
269.30
Half-life
Not established; rapidly degraded in biological systems
Research Score
4.5
Studies
88
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Pro-Gly-Pro?
A collagen-breakdown tripeptide generated during matrix proteolysis, especially from collagen-rich tissues. It is best known as a neutrophil chemoattractant and a biomarker of collagen turnover.
Key Benefits & Mechanisms
collagen turnover biomarker
neutrophil chemotaxis research
ECM remodeling
Research Summary
PGP is a well-documented collagen-derived fragment in inflammation and tissue-remodeling literature. Its biology is most established in ECM degradation, innate immune recruitment, and chronic inflammatory disease models rather than supplementation.
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