GPH
Glycyl-L-prolyl-L-hydroxyproline
Gly-Pro-Hyp Amino Acids · MW: 285.29
Amino Acids
Gly-Pro-Hyp
Molecular Weight
285.29
Half-life
transient; hours
Research Score
4.6
Studies
88
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is GPH?
A collagen-derived tripeptide commonly detected after oral collagen hydrolysate intake. It is studied as a circulating marker peptide and for possible extracellular-matrix signaling.
Key Benefits & Mechanisms
skin support
joint matrix support
wound-healing signaling
Research Summary
Identified in human plasma and urine after collagen peptide ingestion. Preclinical work suggests collagen-derived tripeptides may influence fibroblast activity and matrix-related pathways, but peptide-specific clinical efficacy remains unproven.
Related Peptides
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L-Prolyl-glycyl-L-proline
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Asp-Gly-Glu-Ala
A type I collagen-derived tetrapeptide used in cell-adhesion and bone-biology research. It interacts with collagen-related signaling pathways and is commonly studied in scaffolds and wound-healing models.
Collagen PeptidesGFOGER
Gly-Phe-Hyp-Gly-Glu-Arg
A high-affinity type I collagen integrin-binding motif containing hydroxyproline. It is heavily used in biomaterials to promote cell attachment, osteoblast behavior, and matrix organization.
Collagen PeptidesPH
L-prolyl-L-hydroxyproline
A major bioavailable dipeptide from collagen hydrolysate and gelatin digestion. It has been repeatedly detected in blood after oral collagen intake.
Collagen Peptides