Pituitary Adenylate Cyclase-Activating Polypeptide-38
PACAP-38
38 Amino Acids · MW: 4534.2
Amino Acids
38
Molecular Weight
4534.2
Half-life
minutes
Research Score
4.2
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Pituitary Adenylate Cyclase-Activating Polypeptide-38?
38-aa neuropeptide that couples light input to circadian timing in the suprachiasmatic nucleus. It is widely studied in sleep phase shifting and neuronal plasticity.
Key Benefits & Mechanisms
circadian entrainment
light signaling
sleep phase research
Research Summary
PACAP-38 is a major circadian signaling peptide from retinal and CNS pathways to the SCN. It is important for understanding photic entrainment, jet lag biology, and arousal regulation.
Related Peptides
PACAP-38
Pituitary Adenylate Cyclase-Activating Polypeptide-38 (human PACAP-38)
PACAP-38 is a 38-amino-acid neuropeptide with strong CNS trophic signaling and broad neuroprotective activity. It is studied for effects on memory, neuronal survival, and synaptic plasticity through cAMP and BDNF-related pathways.
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